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Top 5 High-CBD and High-THC Cannabis Strains

Does your medical cannabis regimen require the most CBD or THC? Look no further than these mega-potent strains.

Many people have heard of popular marijuana strains like Strawberry Cough, Skywalker OG, Blue Dream, and Jack Herer. Strains like these have become household names in some circles.

But what are the strongest marijuana strains in the world?

Medical Marijuana, Inc. compiled a list of the most potent strains available. Our list includes old favorites like ChemDog and Cannatonic, and newcomers Desert Ruby, Strawberry Banana, and Cali Cure.

Potent strains, such as those high-CBD and high-THC strains on our list, are valuable to medical cannabis users for a number of reasons. First, they offer more bang for your buck, saving users money in the long run. More potent strains also mean you need to use less flower to achieve your desired effects. Finally, potent strains can save you time, allowing you to get the same effects with a fraction of the effort. Keep reading to discover the most potent medical marijuana strains available.

Highest THC Strains:

According to the Seattle Times, only about 2.5 percent of marijuana in Washington tests above 28 percent THC. All five of the top performers listed here from the past two years worth of worldwide Cannabis Cups scored higher than 31 percent, making them the cream of the crop. These strains pull from some of the most well-known cannabis strains, like OG Kush, Northern Lights, Headband, Durban Poison, and Girl Scout Cookies.


Godfather OG takes the top of our list for strongest THC strains with an incredible 34.04% THC. OG strains have long been prized for their unbelievably relaxing effects, and Godfather OG is no different. Although it has a dubious lineage, with different online sources listing various genetics, most acknowledge it as Granddaddy Purp (GDP) and OG Kush.

There is a spiciness in its scent that should be familiar to OG Kush connoisseurs that’s coupled with some subtle grape notes from the GDP. One of the heavier OG strains available, Godfather OG is best used after physical activities and is often recommended for users hoping to get a good night’s sleep.

Northern lights strain genetics


Named for its ability to glue you to your seat, Super Glue is a cross between strains like Afghani and Northern Lights. Afghani is a heavy-bodied pure indica landrace (domesticated variety) that is from the Hindu Kush mountain region of Afghanistan. Northern Lights itself is a cross of the same Afghani and a Thai sativa landrace.

Super Glue’s pale, frosty buds have flavor profiles that vary from pine and pungent earth to a sour, acidic citrus. Super Glue brings calming relaxation to the mind and body. Watch out for “couchlock” when consumed in high amounts, which can keep you from being productive. Typically found with THC percentages in the low 20s, this hitter reached 32.14% at the 2016 Southern California Cannabis Cup.


ChemDog’s ultimate genetics are a mystery, with many breeders claiming to have had a hand in its creation. Many believe its heritage originates in Eastern Asia (Thai and Nepalese) landraces. ChemDog is a sativa-dominant hybrid with THC levels regularly reaching into 20% or higher. At the Colorado Cannabis Cup, this strain came in at 32.12% THC. Buds of ChemDog are usually sticky with resin. ChemDog’s name comes from the strain’s strong, diesel fuel-like scent and similarly sharply astringent flavor.

Also known as ChemDawg, this old school strain is rumored to provide parent genetics to a number of respected strains, including OG Kush and Sour Diesel. The most sought after descendent of this strain is ChemDawg 91, thought to be closest to the original cut. The relaxed, mood lifting high is sure to pull you out of any funk and get you moving day and night.


Developed by DNA Genetics in collaboration with Serious Seeds, Strawberry Banana is a 70/30 indica-dominant gem that tested at 31.62%. Strawberry Banana is a genetic cross between Crockett’s Banana Kush and a Strawberry scented phenotype of Bubble Gum, inheriting the fruity sweet flavor that earned this hybrid its name. Known for its heavy resin production and high THC content, this strain is popularly used in making extracts.

Strawberry Banana produces peaceful effects that heighten creativity and alter the senses, perfect for watching a movie or having a craft night. Its cerebral effects are secondary, but surprisingly introspective. Sedative and relaxing, Strawberry Banana’s full body effects come on slowly but dominate the high.

Girl Scout Cookies marijuana strain


The Denver Cannabis Cup’s 2016 Strongest THC Strain with 31.1%, this Los Angeles bred strain is a cross of Emperor OG (Headband x OG Kush) and the ever popular Girl Scout Cookies (OG Kush x Durban Poison). Emperor Cookies Dough’s high testing numbers shouldn’t come as a surprise. The strain regularly hits high 20s in THC concentration and up to 5% CBD.

Emperor Cookie Dough has a sweet, nutty flavor, accentuated by hints of citrus and diesel. With OG Kush genetics, you can expect a relaxed and happy high. Emperor Cookie Dough will leave you daydreamy and thoughtful, with cerebral effects thanks to the Durban Poison.

CBD dominant medical marijuana strains

Highest CBD Strains

Once ignored by the marijuana community, CBD had been systematically bred out of the cannabis plant’s cannabinoid profile by growers favoring high THC strains that sold better to recreational users. High CBD strains like those listed below are now gaining popularity for their balanced highs, less sharp cerebral effects, and strong physical benefits.

Once a rarity on dispensary shelves, CBD-dominant strains are now earning their place alongside high-THC strains at events like the Cannabis Cup. The strains on this list have genetics from the best known CBD strains available, including Harlequin, AC/DC, and Sour Tsunami. While it is often accepted that a 1:1 ratio of CBD to THC is the most comfortable high, higher ratios, reaching up to 24:1, provide wellness effects with minimal, if any, psychoactivity.

MK Ultra CIA program medical marijuana


A popular medical marijuana strain, Cannatonic is a cross between MK Ultra and G13 Haze that was developed to maximize each strain’s indica characteristics. Most phenotypes of Cannatonic present with a slight earthy flavor, accented by sweet pine and citrus.

Cannatonic typically tests at about 12% CBD with a 1:1 or 2:1 CBD to THC ratio but scored 22.77% CBD when tested for the 2016 Southern California Cannabis Cup.

The effects can be powerful, but short lived. The effect is mostly physical with a clear headed high, making it good for daytime relief when you are expected to function. The focus here is on relaxation and wellbeing. This is a feel good strain that has gained popularity in the cannabis community worldwide despite – or perhaps because of – its high CBD content.


This CBD-rich strain was named for the late Lawrence Ringo, a cannabis activist and pioneer of CBD-rich strains. Ringo’s Gift crosses Harle-Tsu, a high-CBD hybrid cross between Harlequin and Sour Tsunami, and ACDC, a Cannatonic phenotype. Ringo’s Gift reached 20.23% in Southern California.

Dominant flavors are citrus and pine, with a noticeable earthiness that sits deep in the nose when inhaled. Phenotypes of Ringo’s Gift vary wildly in CBD to THC ratios from 1:1 to 24:1. With such a range in CBD ratio, effects can be hard to nail down. Most harvests will provide a mellow mix of cerebral stimulation and soothing, full-body relaxation without the “couch lock” effect tied to some cannabis strains.

GSC OG Kush California cannabis strains


Bred by Hermosa Seeds, Cali Cure has mostly Critical Cure lineage with influence from OG Kush and Girl Scout Cookies. Strongly indica dominant, Cali Cure won Best CBD Flower at the 2016 Southern California Cannabis Cup and came in 2nd in potency with 19.92% CBD.

Cali Cure typically presents a 2:1 CBD to THC ratio for soothing body effects that are perfect for immediately after rigorous activity. Expect fragrant sweet floral scent and flavor for a delightful smoking experience.


A localized strain just coming to popularity in Colorado, Desert Ruby is the brainchild of NectarBee, the in-house brand for The Green Solution chain of dispensaries dotting Colorado.

NectarBee dominated the Denver Cannabis Cup in 2016.

Little is known about Desert Ruby beyond its 17.48% CBD concentration. It has won Best CBD Flower and Best CBD Concentrate awards at Denver Cannabis Cups demonstrating its promise as a high-CBD strain.

1:1 to 2:1 CBD THC ratio marijuana strains


An OG Kush and unknown high-CBD strain cross from breeders Dinafem Seeds, OG Kush CBD registers a close 1:1 to 2:1 ratio of CBD to THC. Dinafem reports an average CBD level of 10%, but OG Kush CBD reached 15.9% at the Cannabis Cup. OG Kush CBD has classic OG Kush woody pine and lemon profiles with hints of diesel and warm spices.

A unique strain to try for OG Kush lovers or a more balanced strain for those looking for a CBD strain with equal amounts THC, OG Kush CBD capitalizes on the superior OG name and the growing popularity of CBD for a best-of-both-worlds high.

Finding These Strains

Check with your local dispensaries for these potent strains. If they aren’t available, talk to your budtender about stocking the shelves with these strongest strains in the world.

Learn more about cannabis and strains like these on our Cannabis 101 page.

Medical Marijuana, Inc. determined the highest THC and CBD strains available by pulling from the 2016 and 2017 results of the High Times Cannabis Cup competitions. Average THC and CBD concentrations were compiled from published testing results from labs like Analytical 360.

Post by Jeffrey Stamberger

Jeffrey writes media content covering the latest in news, medical research, policy changes, and product education from the cannabis industry.
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